Johns Hopkins UniversityEst. 1876

America’s First Research University

Back to Results
Cover of "Your Immune System: The Amazing Science of Who You Are" by Gary A. Koretzky, MD, PhD, featuring colorful molecular clusters on a soft gradient background.
Preorder
Cover of "Your Immune System: The Amazing Science of Who You Are" by Gary A. Koretzky, MD, PhD, featuring colorful molecular clusters on a soft gradient background.
Share this Title:

Your Immune System

The Amazing Science of Who You Are

Gary A. Koretzky, MD, PhD

Publication Date

The science behind the extraordinary system that keeps you healthy every day.

The immune system—a network of cells, molecules, and organs working together to defend us—is one of nature's most intricate and awe-inspiring achievements. Your Immune System offers readers an illuminating tour of this vital realm, guided by an accomplished physician-scientist whose career has been devoted to understanding its extraordinary power.

Gary A. Koretzky, MD, PhD, explains the fundamental principles that make immunity possible: the cells that sense and respond to danger, the two arms of the immune system that...

The science behind the extraordinary system that keeps you healthy every day.

The immune system—a network of cells, molecules, and organs working together to defend us—is one of nature's most intricate and awe-inspiring achievements. Your Immune System offers readers an illuminating tour of this vital realm, guided by an accomplished physician-scientist whose career has been devoted to understanding its extraordinary power.

Gary A. Koretzky, MD, PhD, explains the fundamental principles that make immunity possible: the cells that sense and respond to danger, the two arms of the immune system that provide rapid and lasting protection, and the language that allows these components to communicate with precision. He explains how vaccination became humanity's first and most effective means of using immune knowledge to promote health and prevent disease. But what happens when immunity falters or misfires? Koretzky explores immunodeficiencies, in which defenses fail to activate; allergies, when the body mistakes harmless substances for threats; and autoimmune diseases such as rheumatoid arthritis, diabetes, and Myasthenia Gravis, where self-recognition goes tragically awry.

Your Immune System outlines why these conditions arise and why they persist as one of medicine's greatest challenges. Koretzky connects the biological foundation of immunity to modern breakthroughs in diagnosis and therapy that are reshaping the treatment of cancer, autoimmune disorders, and infectious disease. An accessible introduction to the elegance of the immune system, this book invites readers to appreciate the marvel of the body's most complex—and indispensable—protector.

Reviews

Reviews

A microscopic army swarms through our bodies, repelling foreign invaders, destroying infected or cancerous cells, and clearing debris. Your Immune System relates, in clear, accessible language, how scientists painstakingly discovered this complicated organ, and how it works. A must-read for anyone interested in health, disease, or prevention.

An absolutely wonderful and very timely book by Dr. Gary Koretzky that lays bare the mysteries of our amazing immune response in a manner that is accessible and understandable by all.

A great challenge for science communication is doing justice to the complexity and detail of science, while shaping a compelling, engaging, and accessible narrative. This book is a rare achievement. It invites our curiosity about how the immune system works without sacrificing any of the rigor.

In his new book, Your immune System, Gary Koretzky does a great job making the complexities of immunology accessible to a broad audience. I especially love how he highlights the history of the research that led us to our present understanding and the scientists whose contributions were essential to this understanding.

Your Immune System takes the reader on a fascinating journey through the history of immunology: from the basic workings of the immune system to how things go awry in allergy, immunodeficiency, and autoimmunity, to the modern-day discoveries of how scientists have learned to harness the power of immunology to prevent, treat and potentially cure human disease. An inspiring account by a master clinician and immunologist.

See All Reviews
About

Book Details

Release Date
Publication Date
Status
Preorder
Trim Size
6
x
9
Pages
400
ISBN
9781421455143
Illustration Description
17 b&w illus.
Table of Contents

Contents
List of Illustrations
Introduction
Part I. The Basics of the Human Immune System
Chapter 1
The Fundamental Principles of Immunity
Chapter 2
The Innate and Adaptive Immune Systems
Chapter 3
Antibodi

Contents
List of Illustrations
Introduction
Part I. The Basics of the Human Immune System
Chapter 1
The Fundamental Principles of Immunity
Chapter 2
The Innate and Adaptive Immune Systems
Chapter 3
Antibodies, Diversity, and the B Cell Antigen Receptor
Chapter 4
Transplantation and Explorations into T Cells
Chapter 5
Putting It All Together
A Case of COVID-19
Chapter 6
Allergy
From an Inconvenience to a Life-Threatening Emergency
Chapter 7
Balancing Immune Responses
Part II. Passive and Active Immunization
Chapter 8
Therapeutic Antibodies
Chapter 9
Early Vaccine Successes
Chapter 10
The Modern Era of Vaccination
Part III. Immunodeficiencies and Autoimmunity
Chapter 11
Congenital Immunodeficiencies
Chapter 12
Acquired Immunodeficiencies
Chapter 13
Recognizing Self, Part 1
Central T Cell Tolerance
Chapter 14
Recognizing Self, Part 2
Peripheral T Cell Tolerance
Chapter 15
Autoimmunity in Adults
Nature plus Nurture
Chapter 16
Four Pathways to Autoimmunity
Part IV. The Immunotherapy Revolution: Suppressing and Augmenting Immune Cell Function
Chapter 17
From Basic Immunology to Patient Care
Chapter 18
Five New Approaches to Suppressing Immune Responses
Chapter 19
Early Approaches to Treating Cancer
Chapter 20
Cancer Immunotherapy in 2025
Epilogue
Acknowledgments
Glossary
Notes
Index

Author Bio
Gary Alan Koretzky, M.D.
Featured Contributor

Gary Alan Koretzky, M.D.

Gary A. Koretzky, MD, PhD, is an emeritus professor of medicine at Weill Cornell Medical and an emeritus professor of microbiology and immunology at the Cornell College of Veterinary Medicine.