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Mechanism, Experiment, Disease

Marcello Malpighi and Seventeenth-Century Anatomy

Domenico Bertoloni Meli

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A leading early modern anatomist and physician, Marcello Malpighi often compared himself to that period’s other great mind—Galileo. Domenico Bertoloni Meli here explores Malpighi’s work and places it in the context of seventeenth-century intellectual life.

Malpighi’s interests were wide and varied. As a professor at the University of Bologna, he confirmed William Harvey’s theory of the circulation of blood; published groundbreaking studies of human organs; made important discoveries about the anatomy of silkworms; and examined the properties of plants. He sought to apply his findings to medical...

A leading early modern anatomist and physician, Marcello Malpighi often compared himself to that period’s other great mind—Galileo. Domenico Bertoloni Meli here explores Malpighi’s work and places it in the context of seventeenth-century intellectual life.

Malpighi’s interests were wide and varied. As a professor at the University of Bologna, he confirmed William Harvey’s theory of the circulation of blood; published groundbreaking studies of human organs; made important discoveries about the anatomy of silkworms; and examined the properties of plants. He sought to apply his findings to medical practice. By analyzing Malpighi’s work, the author provides novel perspectives not only on the history of anatomy but also on the histories of science, philosophy, and medicine. Through the lens of Malpighi and his work, Bertoloni Meli investigates a range of important themes, from sense perception to the meaning of Galenism in the seventeenth century.

Bertoloni Meli contends that to study science and medicine in the seventeenth century one needs to understand how scholars and ideas crossed disciplinary boundaries. He examines Malpighi’s work within this context, describing how anatomical knowledge was achieved and transmitted and how those processes interacted with the experimental and mechanical philosophies, natural history, and medical practice.

Malpighi was central in all of these developments, and his work helped redefine the intellectual horizon of the time. Bertoloni Meli’s critical study of this key figure and the works of his contemporaries—including Borelli, Swammerdam, Redi, and Ruysch—opens a wonderful window onto the scientific and medical worlds of the seventeenth century.

Reviews

Reviews

The strength of Meli's work lies in his attention to detail in highly complex Latin works, and in his sensitivity to unpublished work, correspondence, diaries, and above all, to the technologies of illustration.

Bertoloni Meli makes great use of Malpighi's wonderful epistolary consultations to remind readers that boundaries between research and practice have been drawn too sharply by historians. His use of overlooked medical correspondence increases the presence of Malpighi, the medical practitioner, working from bench to bedside four centuries before translational research hit the headlines.

The most comprehensive account to date of the works of Marcello Malpighi.

Bertoloni Meli's book is a very valuable and welcome contribution to the ongoing reassessment of the Scientific Revolution as a manifold process that involved all areas of natural knowledge—from physics to medicine—and reconfigured each and their mutual relations.

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Book Details

Publication Date
Status
Available
Trim Size
6.125
x
9.25
Pages
456
ISBN
9780801899041
Illustration Description
108 halftones
Table of Contents

Acknowledgments
Introduction: Anatomy, Medicine, and the New Philosophy
1. Anatomical Research in the Second Half of the Seventeenth Century
2. Malpighi's Role on the Anatomical Stage
3. Medical Locations

Acknowledgments
Introduction: Anatomy, Medicine, and the New Philosophy
1. Anatomical Research in the Second Half of the Seventeenth Century
2. Malpighi's Role on the Anatomical Stage
3. Medical Locations: The Sites of Malpighi's Work
4. Mechanism and Mechanics
5. Experiment and Collaboration
6. Disease and Anatomy
7. Structure and Organization
Part I: The Rise of Mechanistic and Microscopic Anatomy: Malpighi's Formation and Association with Borelli
1. The New Anatomy, the Lungs, and Respiration
1.1. Changing Anatomical Horizons
1.2. Malpighi's Bologna Apprenticeship: Anatomical Venues and Vivisection
1.3. Malpighi's Pisa Apprenticeship: Microscopy and the New Philosophy
1.4. Malpighi's Epistolae on the Lungs
1.5. The Purpose of Respiration: Thruston, Lower, and Hooke
2. Epidemic Fevers and the Challenge to Galenism
2.1. Galenic Traditions and New Medical Thinking
2.2. Borelli and the Sicilian Epidemics of 1647–48
2.3. Borelli, Malpighi, and the Pisa Epidemics of 1661
2.4. The 1665 Controversy between the Neoterics and the Galenists
2.5. Malpighi's Risposta to Galenistarum triumphus
3. The Anatomy of the Brain and of the Sensory Organs
3.1. Atomism and the Anatomy of the Senses
3.2. Brain Research in the 1660s: Willis, Steno, and Malpighi
3.3. Malpighi's Anatomical Findings on Taste and Touch
3.4. Fracassati's Far-Reaching Investigations
3.5. Bellini and Rossetti: Atomistic Anatomy of Taste and Touch
Part II: Secretion and the Mechanical Organization of the Body: Glands as the Centerpiece of Malpighi's Investigations
4. The Glandular Structure of the Viscera
4.1. The Revival of Glands
4.2. Changing Perceptions on Glands: Glisson, Wharton, and Steno
4.3. Malpighi's Treatise on the Liver
4.4. The Brain and the Cerebral Cortex
4.5. The Kidneys: Bellini and Malpighi
4.6. The Spleen and Its Problems
5. Fat, Blood, and the Body's Organization
5.1. The Necessity of Matter and the Animal's Benefit
5.2. Descartes on Fat, Blood, and Nutrition
5.3. Malpighi on Fat and Its Philosophical Implications
5.4. Blood Transfusions
5.5. Malpighi on Heart Polyps and the Nature of Blood
6. The Structure of Glands and the Problem of Secretion
6.1. Different Perspectives on Glands
6.2. Intestinal Glands and Their Implications
6.3. The Mode of Operation of Glands
6.4. Glands in the Theatre: Bellini, Sbaraglia, and Malpighi
6.5. Nuck's New Taxonomy of Glands
Part III: Between Anatomy and Natural History: Malpighi andthe Royal Society
7. The Challenge of Insects
7.1. Changing Perceptions on Insects
7.2. Redi: Experiments and Generation
7.3. Malpighi: Historia and Anatomy
7.4. Swammerdam: Metamorphosis and Classification
7.5. Swammerdam and Malpighi: Microstructure and Iconography
8. Generation and the Formation of the Chick in the Egg
8.1. Generation and Its Problems
8.2. Harvey: Epigenesis and the Role of the Faculties
8.3. The Organs of Generation and the Problem of Fecundation
8.4. Swammerdam and the Amsterdam Circle on Preformation
8.5. Malpighi and the Formation of the Chick in the Egg
9. The Anatomy of Plants
9.1. Plants between Anatomy and Natural History
9.2. Malpighi's Anatomy of Plants: Structure, Iconography, and Experiment
9.3. Trionfetti, Malpighi, Cestoni, and the Vegetation of Plants
9.4. Grew and Camerarius: Iconography, "OEconomy," and SexualReproduction
Part IV: Anatomy, Pathology, and Therapy: Malpighi's Posthumous Writings
10. The Fortunes of Malpighi's Mechanistic Anatomy
10.1. Mechanistic Anatomy and Malpighi's Vita
10.2. Writing about the Self
10.3. Levels of Mechanical Explanation in Borelli and Malpighi
10.4. Paolo Mini and the Soul-Body Problem
10.5. Ruysch's Challenge and Boerhaave
11. From the New Anatomy to Pathology and Therapy
11.1. A Bologna Controversy and Its Wider Implications
11.2. Sbaraglia's Challenge to Malpighi's Research
11.3. Malpighi: The Medical Signifi cance of the New Anatomy
11.4. Sbaraglia's Empiricism and Methodological Concerns
11.5. Young Morgagni's Covert Intervention
12. Medical Consultations
12.1. Between Theory and Practice, Carnival and Lent
12.2. Publishing Malpighi's Consultations
12.3. Structure and Contents of Malpighi's Consultations
12.4. Curing with the Pen: Francesco Redi
12.5. A Broader Look at Medical Consultations: Vallisneri and Morgagni
Epilogue
List of Abbreviations
Notes
References
Index

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